Cell Death & Disease

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Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells

Svenja ZielkeNina MeyerMuriel MariKhalil Abou-El-ArdatFulvio ReggioriSjoerd J. L. van WijkDonat KögelSimone Fulda

2018-9-24


Phosphoglycerate dehydrogenase inhibition induces p-mTOR-independent autophagy and promotes multilineage differentiation in embryonal carcinoma stem-like cells

Tanveer SharifEmma MartellCathleen DaiMohammad Saleh Ghassemi-RadKristen LeeSheila K. SinghIan C. G. WeaverShashi Gujar

2018-9-24


RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation

Julian BuchrieserMaria Jose Oliva-MartinMichael D. MooreJoshua C. D. LongSally A. CowleyJose Antonio Perez-SimónWilliam JamesJose Luis Venero

2018-9-24


Sensitizing non-small cell lung cancer to BCL-xL-targeted apoptosis

Qi ShenJun LiJunhua MaiZhe ZhangAndrew FisherXiaoyan WuZhaoqi LiMaricela R. RamirezShuqing ChenHaifa Shen

2018-9-24


Linc02527 promoted autophagy in Intrahepatic cholestasis of pregnancy

Jianguo HuLi LiuYangyang GongLei ZhangXiaoling GanXiaodong LuoTinghe YuXiaocui ZhongXinru DengLina HuZhanyu ZhangXiaojing Dong

2018-9-24


POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling

Yuheng DuDaojiang LiNanpeng LiChen SuChunxing YangChangwei LinMiao ChenRunliu WuXiaorong LiGui Hu

2018-9-24


Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

Sara IachettiniDaniela TrisciuoglioDante RotiliAlessia LucidiErica SalvatiPasquale ZizzaLuca Di LeoDonatella Del BufaloMaria Rosa CirioloCarlo LeonettiClemens SteegbornAntonello MaiAngela RizzoAnnamaria Biroccio

2018-9-24


Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy

Fan YangYing QinJie LvYueqiu WangHui CheXi ChenYanan JiangAnqi LiXi SunEr YueLong RenYang LiYunlong BaiLihong Wang

2018-9-24


C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event

Zachary J. MessengerJonathan R. HallDereje D. JimaJohn S. HouseHann W. TamDebra A. TokarzRobert C. Smart

2018-10-15


Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer

Lusheng WeiHuilin YeGuolin LiYuanting LuQuanbo ZhouShangyou ZhengQing LinYimin LiuZhihua LiRufu Chen

2018-10-18


The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

Sonja HagerKatharina KorbulaBjörn BielecMichael GruschChristine PirkerMarkus SchossererLisa LiendlMagdalena LangJohannes GrillariKarin NowikovskyVeronika F. S. PapeThomas MohrGergely SzakácsBernhard K. KepplerWalter BergerChristian R. KowolPetra Heffeter

2018-10-15


Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation

Zhennan TaoTao LiHaiwen MaYihan YangChen ZhangLong HaiPeidong LiuFeng YuanJiabo LiLi YiLuqing TongYingshuai WangYang XieHaolang MingShengping YuXuejun Yang

2018-10-18


Plasminogen activation is required for the development of radiation-induced dermatitis

Mahsa FallahYue ShenJessica BrodénAssar BäckmanBertil LundskogMichael JohanssonMichael BlomquistKui LiuMalgorzata WilczynskaTor Ny

2018-10-15


Positive feedback loop between mitochondrial fission and Notch signaling promotes survivin-mediated survival of TNBC cells

Li ChenJing ZhangZhuomin LyuYibing ChenXiaoying JiHaiyan CaoMingpeng JinJianjun ZhuJin YangRui LingJinliang XingTingting RenYonggang Lyu

2018-10-15


YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma

Adrian Rivera-ReyesShuai YeGloria E. MarinoShaun EgolfGabrielle E. CiottiSusan ChorYing LiuJessica M. PosimoPaul M. C. ParkKoreana PakYael BabichevJaimarie Sostre-ColónFeven TameireNektaria Maria LeliConstantinos KoumenisDonita C. BradyAnthony MancusoKristy WeberRebecca GladdyJun QiT. S. Karin Eisinger-Mathason

2018-10-31